||Lily of the Valley
||Constancy, Jacob's Ladder, Ladder-to-Heaven, May Lily, Our Lady's Tears.
||Moist, rich soil in shade or partial shade. Rhizomes may be attacked by caterpillars. Leaves have a tendency to develop Botrytis in wet conditions or develop leaf spotting on dry soils in sun.
||By seed sown when ripe; by division after flowering or in autumn. Cultivars do not come from true seed.
||Flowering plants are picked in spring and used fresh or dried in liquid extracts and tinctures. The glycoside content diminishes in the dry leaf. Flowers are collected in spring for extraction of volatile oil.
||Europe, NE Asia
Has golden stripes down the leaves. Tends to revert if grown in deep shade.
Has double flowers.
Is vigorous, with broad leaves and flowers to 1.5cm (½in) across.
Height: 30cm (12in)
Has broad leaves with gold margins and flowers to 1cm (3/8in) across. Forces well.
Height: 25cm (10in)
Has dense spikes of double often slightly malformed flowers.
Has pale mauve-pink-spotted flowers.
||Leaves, flowers, oil, whole plant
||A bitter, diuretic herb that acts as a tonic for the heart and cardiovascular system.
||Internally for congestive heart failure, arteriosclerosis with angina, arterial hypotension, Often combined with Crataegus spp. (See, hawthorn). For use by qualified practitioners only.
To treat stroke, leprosy, heart problems, and epilepsy. Germany's Commission E has approved the use of lily-of-the-valley to treat irregular heartbeat and other heart ailments.
||A typical daily dose of lily-of-the-valley is approximately 600 mg of tincture or liquid extract.
|Possible Side Effects:
||Lily-of-the-Valley's side effects include nausea, vomiting, irregular heartbeat, and headache. Lily-of-the-valley contains cardiac glycosides, which can help control irregular heartbeat, reduce the backup of blood and fluid in the body, and increase blood flow through the kidneys, helping to excrete sodium and relieve swelling in the body tissues. However, a buildup of cardiac glycosides can occur, especially when the herb is combined with certain medications or other herbs that contain cardiac glycosides, causing arrhythmias, abnormally slow heartbeat, heart failure, and even death.
|Taking lily-of-the-valley with these drugs may enhance the therapeutic and/or adverse effects of the drug:
|Betamethasone, (Betatrex, Maxivate)
||Calcium Acetate, (PhosLo)
||Calcium Carbonate, (Rolaids Extra Strength, Tums)
||Calcium Chloride, (Calcium Chloride)
||Calcium Citrate, (Osteocit)
|Calcium Glubionate, (Calcium Glubionate)
||Calcium Gluceptate, (Calcium Gluceptate)
||Calcium Gluconate, (Calcium Gluconate)
|Deflazacort, (Calcort, Dezacor)
||Dexamethazone, (Decadron, Dexasone)
||Digitalis, (Digitek, Lanoxin)
||Docusate, (Colace, Ex-Lax Stool Softener)
||Docusate and Senna, (Peri-Colace, Senokot-S)
|Hydrocortisone, (Cetacort, Locoid)
||Lactulose, (Constulose, Enulose)
||Magnesium Citrate, (Citro-Mag)
||Magnesium Hydroxide, (Dulcolax Milk of Magnesia, Phillips' Milk of Magnesia)
||Magnesium Hydroxide and Mineral Oil, (Phillips' M-O)
|Magnesium Oxide, (Mag-Ox 400, Uro-Mag)
||Magnesium Sulfate, (Epsom Salts)
||Methylprednisolone, (Depo-Medrol, Medrol)
||Polyethyline Glycol-Electrolyte Solution, (Colyte, MiraLax)
||Prednisolone,(Imflamase Forte, Pred Forte)
|Prednisone, (Apo-Prednisone, Deltasone)
||Psyllium, (Metamucil, Reguloid)
||Quinidine, (Novo-Quinidin, Quinaglute Dura-Tabs)
||Triamcinolone, (Aristocort, Trinasal)
|Taking lily-of-the-valley with these drugs may increase the risk of bradycardia (slow heart rate):
|Acebutolol, (Novo-Acebutolol, Sectral)
||Atenolol, (Apo-Atenolol, Tenormin)
||Befunolol, (Bentos, Betaclar)
||Betaxolol, (Betoptic S, Kerlone)
||Bisoprolol, (Monocor, Zebeta)
||Carteolol, (Cartrol, Ocupress)
||Digitalis, (Digitek, Lanoxin)
||Diltiazem, (Cardizem, Tiazac)
||Felodipine, (Plendil, Renedil)
||Labetalol, (Normodyne, Trandate)
|Lacidipine, (Aponil, Caldine)
||Lercanidipine, (Cardiovasc, Carmen)
||Levobunolol, (Betagan, Novo-Levobunolol)
|Manidipine, (Calslot, Iperten)
||Metoprolol, (Betaloc, Lopressor)
||Nadolol, (Apo-Nadol, Corgard)
||Nifedipine, (Adalat CC, Procardia)
||Oxprenolol, (Slow-Trasicor, Trasicor)
|Pindolol, (Apo-Pindol, Novo-Pindol)
||Propanolol, (Inderal, InnoPran XL)
||Sotalol, (Betapace, Sorine)
||Timolol, (Betimol, Timoptic)
|Verapamil, (Calan, Isoptin SR)
|Taking lily-of-the-valley with these drugs may increase the risk of cardiac glycoside toxicity:
|Acetazolamide, (Apo-Acetazolamide, Diamox Sequels)
||Bumetanide, (Bumex, Burinex)
|Chlorthalidone, (Apo-Chlorthalidone, Thalitone)
||Ethacrynic Acid, (Edecrin)
||Furosemide, (Apo-Furosemide, Lasix)
|Hydrochlorothiazide, (Apo-Hydro, Microzide)
||Hydroflumethiazide, (Diucardin, Saluron)
||Indapamide, (Lozol, Nu-Indapamide)
||Mannitol, (Osmitrol, Resectisol)
||Methazolamide, (Apo-Methazolamide, Neptazane)
||Methyclothiazide, (Aquatensen, Enduron)
||Metolazone, (Mykrox, Zaroxolyn)
|Olmesartan and Hydrochlorothiazide, (Benicar HCT)
||Trichlormethiazide, (Metatensin, Naqua)
|Urea, (Amino-Cerv, UltraMide)
||Xipamide, (Diurexan, Lumitens)
- Increased risk of cardiac glycoside toxicity when used with other herbs that contain cardiac glycosides, such as Black Hellebore, Calatropis, Motherwort, and others.
- Increased risk of potassium depletion when used in conjunction with Horsetail Plant or Licorice.
- Increased risk of cardiotoxicity due to potassium depletion when taken with cardioactive herbs, such as Adonis, Digitalis, and Squill.
- Increased risk of potassium depletion when used with stimulant laxative herbs, such as Black Root, Cascara Sagrada, Castor Oil, and Senna.
- Increased action of lily-of-the-valley when taken concurrently with English Hawthorn.
||Volatile oil, rich in farnesol, is used for perfumery and snuff.
||This herb is subject to legal restrictions in some countries.
All parts, especially fruits and seeds, are toxic if eaten.
||Encyclopedia of Herbs by Deni Brown. Copyright © 1995, 2001 Dorling Kindersley Limited. pg 178
The Essential Herb-Drug-Vitamin Interaction Guide by Geo. T. Grossberg,MD and Barry Fox,PhD Copyright©2007 Barry Fox,PhD. Pp.312-314